Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1853237 |
| description: |
epitope description:beta-D-GlcpA-(1->3)-[beta-D-GlcpA-(1->3)-beta-D-GalpNAc-(1->6)]-beta-D-GalpNAc
antigen name:proteoglycan
host organism:Mus musculus BALB/c
antibody name:25–9B10-A, 27–2E2-A
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
12695908 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1006578 |
| landingPage: |
http://www.iedb.org/assay/1853237 |
| type: |
Literature
|
| publicationVenue: |
Parasitol Res
|
| dates: |
2003
|
| study type: | b cell assays |
| subject species: | Schistosoma mansoni |
| fullName: |
H J Vermeer
G J van Dam
K M Halkes
J P Kamerling
J F G Vliegenthart
C H Hokke
A M Deelder
|
| method: |
antigen inhibition
|
| name: |
Immunodiagnostically applicable monoclonal antibodies to the circulating anodic antigen of Schistosoma mansoni bind to small, defined oligosaccharide epitopes.
|
| description: |
The epitope is part of the O-glycans of circulating anodic antigen (CAA), a proteoglycan with a strong negative charge at neutral pH, of S. mansoni.
The trichloroacetic acid treated adult worm antigen (AWA-TCA, which contains native CAA) competed with the epitope for the binding to the epitope-specific mAbs. The IC50 values were 3 ug/ml of AWA for mAb 27-2E2-A and 1.9 ug/ml for mAb 25-9B10-A.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
