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identifier: 1853706
description:
epitope description:L51, P93, R140, P143, G144, H145, K148, E152, E157, F160, K176, E177, D178, E179, L180, G181, D182, R183, M186
antigen name:Interleukin-18
host organism:Mus musculus BALB/c
antibody name:125-2H
aggregation:
instance of dataset
availability:
available
primaryPublications: 19553661
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1016492
landingPage: http://www.iedb.org/assay/1853706
type:
Literature
publicationVenue:
J Biol Chem
dates:
2009
study type: b cell assays
subject species: Homo sapiens
fullName:
Maria A Argiriadi
Tao Xiang
Chengbin Wu
Tariq Ghayur
David W Borhani
method:
ELISA
name:
Unusual water-mediated antigenic recognition of the proinflammatory cytokine interleukin-18.
description:
The epitope residues are calculated from [PDB: 2VXT] as the antigen residues at he 4Å
atomic distance from the antibody.
The epitope-specific monoclonal antibody bound the peptide from human IL-18 as a part of a fusion protein with mouse IL-18 to which the monoclonal antibody does not bind.

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