Mechanisms of allergen-antibody interaction of cockroach allergen Bla g 2 with monoclonal antibodies that inhibit IgE antibody binding.

Title:

Mechanisms of allergen-antibody interaction of cockroach allergen Bla g 2 with monoclonal antibodies that inhibit IgE antibody binding.

identifier:	1854997
description:	epitope description:K87, R107, K156 antigen name:Bla g 2 host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	21789239

study type:	b cell assays
subject species:	Blattella germanica

fullName:	Jill Glesner Sabina Wü nschmann Mi Li Alla Gustchina Alexander Wlodawer Martin Himly Martin D Chapman Anna Pomé s

method:	ELISA

name:	Mechanisms of allergen-antibody interaction of cockroach allergen Bla g 2 with monoclonal antibodies that inhibit IgE antibody binding.
description:	The epitopic residues were shown to be important for allergic patients' IgE binding because single alanine Bla g 2 mutants K65A, R83A, or K132A displayed reduced IgE binding.

name:	iedb
homePage:	http://www.iedb.org

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