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identifier: 1857083
description:
epitope description:[2)-beta-QuiN4Fm-(1->4)-alpha-GalNAcAN-(1->4)-alpha-GalNAcAN-(1->3)-beta-QuiNAc-(1->]n
antigen name:lipopolysaccharide
host organism:Mus musculus BALB/c
antibody name:FB11
aggregation:
instance of dataset
availability:
available
primaryPublications: 21466282
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1021611
landingPage: http://www.iedb.org/assay/1857083
type:
Literature
publicationVenue:
Hybridoma (Larchmt)
dates:
2011
study type: b cell assays
subject species: Francisella tularensis subsp. holarctica LVS
fullName:
Marly I Roche
Zhaohua Lu
Julia H Hui
Jacqueline Sharon
method:
ELISA
name:
Characterization of monoclonal antibodies to terminal and internal O-antigen epitopes of Francisella tularensis lipopolysaccharide.
description:
The anomeric configuration of the O-PS repeating unit was taken from cited reference, Gunn and Ernst, Ann N Y Acad Sci. 2007
1105:202 [PMID:17395723].
The epitope-specific mAb bound to LPS from F. tularensis holarctica strain LVS. Similar results were observed in Western blot, in which the mAb bound with equal intensity to all sizes of LPS chains, suggesting the mAb binds to a terminal region of OAg.

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