Preclinical study of influenza virus A M2 peptide conjugate vaccines in mice, ferrets, and rhesus monkeys.

Title:

Preclinical study of influenza virus A M2 peptide conjugate vaccines in mice, ferrets, and rhesus monkeys.

identifier:	1857717
description:	epitope description:MSLLTEVETPIRNEWGCRCNDSSD antigen name:Matrix protein 2 host organism:Mus musculus BALB/c
aggregation:	instance of dataset
availability:	available
primaryPublications:	15297047

study type:	b cell assays
subject species:	Influenza A virus (A/Aichi/2/1968(H3N2))

fullName:	Jiang Fan Xiaoping Liang Melanie S Horton Helen C Perry Michael P Citron Gwen J Heidecker Tong-Ming Fu Joseph Joyce Craig T Przysiecki Paul M Keller Victor M Garsky Roxana Ionescu Yvette Rippeon Li Shi Michael A Chastain Jon H Condra Mary-Ellen Davies Jason Liao Emilio A Emini John W Shiver

method:	in vivo assay

name:	Preclinical study of influenza virus A M2 peptide conjugate vaccines in mice, ferrets, and rhesus monkeys.
description:	The epitope conjugated to KLH protected mice from infection with HKxPR8(H3N1) as measured by weight change, mortality, nasal and lung wash viral titers at the respective time points (at day 1, 3, 5, 7 and 9 after HKxPR8 virus challenge).

name:	iedb
homePage:	http://www.iedb.org

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