A common NH53K mutation in the combining site of antibodies raised against chlamydial LPS glycoconjugates significantly increases avidity.

Title:

A common NH53K mutation in the combining site of antibodies raised against chlamydial LPS glycoconjugates significantly increases avidity.

identifier:	1857739
description:	epitope description:alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo antigen name:lipopolysaccharide host organism:Mus musculus BALB/c antibody name:S25-2
aggregation:	instance of dataset
availability:	available
primaryPublications:	21405106

study type:	b cell assays
subject species:	Chlamydiae

fullName:	Ryan J Blackler Sven Mü ller-Loennies Cory L Brooks Dylan W Evans Lore Brade Paul Kosma Helmut Brade Stephen V Evans

method:	ELISA

name:	A common NH53K mutation in the combining site of antibodies raised against chlamydial LPS glycoconjugates significantly increases avidity.
description:	The epitope-specific mAb reacted with the related structure Kdo-(2-8)-Kdo-(2-4)-Kdo-(2-6)-beta-GlcNAc4P-(1-6)-alpha-GlcNAc1P-BSA conjugate in ELISA not as strongly as with the epitope

name:	iedb
homePage:	http://www.iedb.org

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