Crystal structure of vascular endothelial growth factor-B in complex with a neutralising antibody Fab fragment.

Title:

Crystal structure of vascular endothelial growth factor-B in complex with a neutralising antibody Fab fragment.

identifier:	1857753
description:	epitope description:A: S37, W38, I39, Y42, T46, C47, Q48, P83, C122, E123, C124; B: V69, P70, Q100, L102, I104, S108, S109, L111; antigen name:Vascular endothelial growth factor B host organism:Mus musculus antibody name:2H10, neutralizing anti-VEGF-B
aggregation:	instance of dataset
availability:	available
primaryPublications:	18930733

study type:	b cell assays
subject species:	Homo sapiens

fullName:	Philip Leonard Pierre D Scotney Talat Jabeen Shalini Iyer Louis J Fabri Andrew D Nash K Ravi Acharya

method:	surface plasmon resonance (SPR)

name:	Crystal structure of vascular endothelial growth factor-B in complex with a neutralising antibody Fab fragment.
description:	The epitope-specific 2H10 mAb (Ka = 1.52 x 10⁶M^-1s^-1) bound VEGF-B(10-108) with a slighter lower association rate than Fab-2H10 (Ka = 2.27 x 10⁶M^-1s^-1).

name:	iedb
homePage:	http://www.iedb.org

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