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Title: Bactericidal monoclonal antibodies that define unique meningococcal B polysaccharide epitopes that do not cross-react with human polysialic acid.
identifier: 1862586
description:
epitope description:[8)-alpha-Neu5Pr-(2->]n
host organism:Mus musculus CD1
antibody name:SEAM 17
aggregation:
instance of dataset
availability:
available
primaryPublications: 9590252
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1018475
landingPage: http://www.iedb.org/assay/1862586
type:
Literature
publicationVenue:
J Immunol
dates:
1998
study type: b cell assays
subject species:
fullName:
D M Granoff
A Bartoloni
S Ricci
E Gallo
D Rosa
N Ravenscroft
V Guarnieri
R C Seid
A Shan
W R Usinger
S
Y E McHugh
G R Moe
method:
antigen inhibition
name:
Bactericidal monoclonal antibodies that define unique meningococcal B polysaccharide epitopes that do not cross-react with human polysialic acid.
description:
The epitope was generated by substitution of N-propionyl for N-acetyl groups on the meningococcal B polysaccharide.
The epitope inhibited epitope-specific mAb(s) from binding to the epitope. Direct binding to the epitope was also observed by direct ELISA.

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