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identifier: 1858334
description:
epitope description:alpha-Kdo-(2->8)-alpha-Kdo
antigen name:lipopolysaccharide
host organism:Mus musculus BALB/c
antibody name:S67-27
aggregation:
instance of dataset
availability:
available
primaryPublications: 19767317
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1017762
landingPage: http://www.iedb.org/assay/1858334
type:
Literature
publicationVenue:
Glycobiology
dates:
2010
study type: b cell assays
subject species: Bacteria
fullName:
Cory L Brooks
Ryan J Blackler
Georg Sixta
Paul Kosma
Sven Mü
ller-Loennies
Lore Brade
Tomoko Hirama
C Roger MacKenzie
Helmut Brade
Stephen V Evans
method:
surface plasmon resonance (SPR)
name:
The role of CDR H3 in antibody recognition of a synthetic analog of a lipopolysaccharide antigen.
description:
The epitope reactive S67-27 Fab bound to the analog Kdo(2->8)-7-O-Me-Kdo with higher affinity than to the epitope. The solution affinity was determined by surface plasmon resonance from the inhibition of S67-27 Fab binding to immobilized Kdo(2->8) Kdo(2->4)Kdo-BSA.

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