An agonist-like monoclonal antibody against the human beta2-adrenoceptor. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

An agonist-like monoclonal antibody against the human beta2-adrenoceptor.

Dataset

identifier:	1859483
description:	epitope description:WYRATHQE antigen name:Beta-2 adrenergic receptor host organism:Mus musculus BALB/c antibody name:6H8
aggregation:	instance of dataset
availability:	available
primaryPublications:	9650839

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1003906
landingPage:	http://www.iedb.org/assay/1859483

Publication

type:	Literature
publicationVenue:	Eur J Pharmacol
dates:	1998

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	D Lebesgue G Wallukat A Mijares C Granier J Argibay J Hoebeke

Data Type

method:	antigen inhibition

Study

name:	An agonist-like monoclonal antibody against the human beta2-adrenoceptor.
description:	The epitope was deduced. The ß₂R peptide inhibited binding of the epitope-specific monoclonal antibody to the ß₂ adrenergic receptor, inhibiting an increase in beats per minute by neonatal rat cardiomyocytes. Direct binding of the epitope-specific monoclonal antibody to ß₂R peptide was shown by ELISA assay.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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