Protective meningococcal capsular polysaccharide epitopes and the role of O acetylation. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Protective meningococcal capsular polysaccharide epitopes and the role of O acetylation.

Dataset

identifier:	1859100
description:	epitope description:[9)-alpha-Neu5Ac-(2->]n antigen name:polysaccharide host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	17376859

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1004958
landingPage:	http://www.iedb.org/assay/1859100

Publication

type:	Literature
publicationVenue:	Clin Vaccine Immunol
dates:	2007

Dimension

study type:	b cell assays
subject species:	Neisseria meningitidis serogroup C

Person

fullName:	Peter C Fusco Esmé K Farley Chun-Hsien Huang Samuel Moore Francis Michon

Data Type

method:	antigen inhibition

Study

name:	Protective meningococcal capsular polysaccharide epitopes and the role of O acetylation.
description:	The acetylated repetitive region of PS weakly inhibited the serum bactericidal activity against Neisseria meningitidis serogroup C strain C11 of human anti-deacetylatedPS sera. Similar results were observed in sera from vaccinated infants.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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