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identifier: 1859283
description:
epitope description:alpha-D-Glcp-(1->3)-[alpha-D-Glcp-(1->3)-alpha-D-GalpNAc-(1->4)-alpha-D-Glcp-(1->4)]-alpha-D-GalpNAc-(1->4)-alpha-D-Manp
antigen name:polysaccharide
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 21609839
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1022026
landingPage: http://www.iedb.org/assay/1859283
type:
Literature
publicationVenue:
Chem Biol
dates:
2011
study type: b cell assays
subject species: Clostridium difficile BI / NAP1/ 027
fullName:
Matthias A Oberli
Marie-Lyn Hecht
Pascal Bindschä
dler
Alexander Adibekian
Thomas Adam
Peter H Seeberger
method:
ELISA
name:
A possible oligosaccharide-conjugate vaccine candidate for Clostridium difficile is antigenic and immunogenic.
description:
ELISA was performed over a Glycan microarrey. Two patients with significantly increased C. difficile toxin A/B levels and one patient with a borderline test displayed high amounts of highly specific anti-epitope IgA antibodies in their excrement. The other 3 toxin positive patients were negative for anti-epitope antibodies.

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