Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1861070 |
| description: |
epitope description:L78, F79, E82, V83, Q85, K86, V87, K88, C94, N96, P122, G125, Q126, V127, A128, V129, I130, H131, G132
antigen name:MP18 RNA editing complex protein
host organism:Lama glama
antibody name:Nb5
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
20969962 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1022174 |
| landingPage: |
http://www.iedb.org/assay/1861070 |
| type: |
Literature
|
| publicationVenue: |
J Struct Biol
|
| dates: |
2011
|
| study type: | b cell assays |
| subject species: | Trypanosoma brucei |
| fullName: |
Meiting Wu
Young-Jun Park
Els Pardon
Stewart Turley
Andrew Hayhurst
Junpeng Deng
Jan Steyaert
Wim G J Hol
|
| method: |
x-ray crystallography
|
| name: |
Structures of a key interaction protein from the Trypanosoma brucei editosome in complex with single domain antibodies.
|
| description: |
The epitope of nanobody Nb5 on KREPRA6 was determined from the crystal structure of the complex. There are two KREPA6 and two Nb5 chains per asymmetric unit, with KREPA6 forming a dimer (that is the nanobody binds the dimer while the antigen exists in solution as a tetramer).
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
