Autoantigen discovery with a synthetic human peptidome. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Autoantigen discovery with a synthetic human peptidome.

Dataset

identifier:	1859955
description:	epitope description:NEDAVQGIADWDAAQGIADGVAAQGIALDDAVHGIA antigen name:Other Homo sapiens (human) protein host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	21602805

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1022015
landingPage:	http://www.iedb.org/assay/1859955

Publication

type:	Literature
publicationVenue:	Nat Biotechnol
dates:	2011

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	H Benjamin Larman Zhenming Zhao Uri Laserson Mamie Z Li Alberto Ciccia M Angelica Martinez Gakidis George M Church Santosh Kesari Emily M Leproust Nicole L Solimini Stephen J Elledge

Data Type

method:	phage display

Study

name:	Autoantigen discovery with a synthetic human peptidome.
description:	The epitope was identified from the T7 phage display library composed of >413,000 36-residue, overlapping peptides that cover all open reading frames in the human genome. A phage immunoprecipitation sequencing (PhIP-Seq) methodology was applied to identify autoantibodies contained in the spinal fluid of three individuals with paraneoplastic neurological syndromes.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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