| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1008004 |
| landingPage: |
http://www.iedb.org/assay/1861107 |
| type: |
Literature
|
| publicationVenue: |
Infect Immun
|
| dates: |
2005
|
| study type: | b cell assays |
| subject species: |
| fullName: |
Gregory R Moe
Apurva Dave
Dan M Granoff
|
| method: |
biological activity
|
| name: |
Epitopes recognized by a nonautoreactive murine anti-N-propionyl meningococcal group B polysaccharide monoclonal antibody.
|
| description: |
The epitope structure depicts an N-propionated neuraminic acid polymer that is obtained by deacetylation and propionation of the natural meningococcal group B polysaccharide.
The epitope-specific mAb is bactericidal in the presence of complement. The concentration of mAb required for 50% killing of a representative encapsulated N. meningitidis group B strain (8047) is 0.2 ug/ml.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |