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identifier: 1861107
description:
epitope description:[8)-alpha-Neu5Pr-(2->]n
host organism:Mus musculus CD1
antibody name:SEAM 3
aggregation:
instance of dataset
availability:
available
primaryPublications: 15784554
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1008004
landingPage: http://www.iedb.org/assay/1861107
type:
Literature
publicationVenue:
Infect Immun
dates:
2005
study type: b cell assays
subject species:
fullName:
Gregory R Moe
Apurva Dave
Dan M Granoff
method:
biological activity
name:
Epitopes recognized by a nonautoreactive murine anti-N-propionyl meningococcal group B polysaccharide monoclonal antibody.
description:
The epitope structure depicts an N-propionated neuraminic acid polymer that is obtained by deacetylation and propionation of the natural meningococcal group B polysaccharide.
The epitope-specific mAb is bactericidal in the presence of complement. The concentration of mAb required for 50% killing of a representative encapsulated N. meningitidis group B strain (8047) is 0.2 ug/ml.

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