Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1864583 |
| description: |
epitope description:N-{1-amino-6-[(5-nitro-2-furoyl)amino]-1-oxohexan-2-yl}-26-(indol-3-yl)-23-oxo-4,7,10,13,16,19-hexaoxa-22-azahexacosan-1-amide
host organism:Mus musculus
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
21944756 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1022450 |
| landingPage: |
http://www.iedb.org/assay/1864583 |
| type: |
Literature
|
| publicationVenue: |
Chem Biol
|
| dates: |
2011
|
| study type: | b cell assays |
| subject species: |
| fullName: |
Michael W Handlogten
Tanyel Kiziltepe
Demetri T Moustakas
Başar Bilgiç
er
|
| method: |
antigen inhibition (~ IC50)
|
| name: |
Design of a heterobivalent ligand to inhibit IgE clustering on mast cells.
|
| description: |
The epitope was able to inhibit binding of the anti-DNP mAb to epitope-BSA. The antigen also inhibited mast cell degranulation by the epitope-specific mAb in a rat basophilic leukemia cell model.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
