Development of a novel radioimmunoassay to detect autoantibodies to amyloid beta peptides in the presence of a cross-reactive therapeutic antibody.

Title:

Development of a novel radioimmunoassay to detect autoantibodies to amyloid beta peptides in the presence of a cross-reactive therapeutic antibody.

Dataset

identifier:	1862678
description:	epitope description:GLMVGGVV antigen name:Amyloid beta A4 protein host organism:Mus musculus antibody name:2G3
aggregation:	instance of dataset
availability:	available
primaryPublications:	21868184

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1022451
landingPage:	http://www.iedb.org/assay/1862678

Publication

type:	Literature
publicationVenue:	J Pharm Biomed Anal
dates:	2011

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	John H Sloan Bradley J Ackermann Mark O'Dell Ronald R Bowsher Robert A Dean Robert J Konrad

Data Type

method:	radio immuno assay (RIA)

Study

name:	Development of a novel radioimmunoassay to detect autoantibodies to amyloid beta peptides in the presence of a cross-reactive therapeutic antibody.
description:	The epitope-specific mAb recognized the A beta 1-40 peptide in RIA. A mutated peptide with a F19A substitution was recognized equally well.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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