Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1863515 |
| description: |
epitope description:R89, K90, A93, Q96, T97, A174, H175, Q179, A182, Y183, T187, E190, W191
antigen name:HLA class I histocompatibility antigen, A-2 alpha chain
host organism:Homo sapiens
antibody name:3M4E5
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
19307587 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1019713 |
| landingPage: |
http://www.iedb.org/assay/1863515 |
| type: |
Literature
|
| publicationVenue: |
Proc Natl Acad Sci U S A
|
| dates: |
2009
|
| study type: | b cell assays |
| subject species: | Homo sapiens |
| fullName: |
Guillaume Stewart-Jones
Andreas Wadle
Anja Hombach
Eugene Shenderov
Gerhard Held
Eliane Fischer
Sascha Kleber
Natko Nuber
Frank Stenner-Liewen
Stefan Bauer
Andrew McMichael
Alexander Knuth
Hinrich Abken
Andreas A Hombach
Vincenzo Cerundolo
E Yvonne Jones
Christoph Renner
|
| method: |
surface plasmon resonance (SPR)
|
| name: |
Rational development of high-affinity T-cell receptor-like antibodies.
|
| description: |
The epitope-reactive Fab 3M4E5 bound to the NY-ESO-1(157-165)/HLA-A*0201 complex with moderate affinity. The off-rate for the complex containing the natural peptide NY-ESO-1(157-165) with a Cys at position 9 or the analog peptide with a Val at position 9 were similar, kd = 0.004225 versus 0.00362 s^-1, respectively.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
