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Title: Hepatitis B virus surface antigen (HBsAg) as carrier for synthetic peptides having an attached hydrophobic tail.
identifier: 1864285
description:
epitope description:MGTNLSVPNPLGFFPDHQLDPAFGANSNNPDWDFNP
antigen name:Large envelope protein
host organism:Oryctolagus cuniculus
aggregation:
instance of dataset
availability:
available
primaryPublications: 2467197
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1022482
landingPage: http://www.iedb.org/assay/1864285
type:
Literature
publicationVenue:
Mol Immunol
dates:
1989
study type: b cell assays
subject species: Hepatitis B virus subtype adw2
fullName:
A R Neurath
N Strick
M Girard
method:
radio immuno assay (RIA)
name:
Hepatitis B virus surface antigen (HBsAg) as carrier for synthetic peptides having an attached hydrophobic tail.
description:
The epitope sequence is from the reference: Neurath et al. (1988) Ann Inst Pasteur/ virol 139: 13-38 [PMID: 2462893].
The myristylated epitope derivatized to hepatitis B surface antigen synthesized in CHO cells and containing preS2 sequences elicited antibodies to the epitope. The free epitope in CFA or the myristylated peptide in IFA also elicited antibodies to the epitope. The unmodified epitope chemically linked to CHO-HBsAg did not elicit antibodies to the epitope.

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