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identifier: 1898657
description:
epitope description:EASNCF
antigen name:Integral membrane protein 2B
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 19581601
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1016460
landingPage: http://www.iedb.org/assay/1898657
type:
Literature
publicationVenue:
Proc Natl Acad Sci U S A
dates:
2009
study type: b cell assays
subject species: Homo sapiens
fullName:
M Britschgi
C E Olin
H T Johns
Y
M C LeMieux
K Rufibach
J Rajadas
H Zhang
B Tomooka
W H Robinson
C M Clark
A M Fagan
D R Galasko
D M Holtzman
M Jutel
J A Kaye
C A Lemere
J Leszek
G Li
E R Peskind
J F Quinn
J A Yesavage
J A Ghiso
method:
microarray
name:
Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease.
description:
Human IgG reactivities against peptides preparations were measured with antigen microarrays in plasma from healthy female subjects ages 21-85. Antibody reactivities against several amyloidogenic beta amyloid mutant and non-beta amyloid peptides (oligomeric forms) are reduced with age.

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