Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1016460 |
| landingPage: |
http://www.iedb.org/assay/1898679 |
| type: |
Literature
|
| publicationVenue: |
Proc Natl Acad Sci U S A
|
| dates: |
2009
|
| study type: | b cell assays |
| subject species: | Homo sapiens |
| fullName: |
M Britschgi
C E Olin
H T Johns
Y
M C LeMieux
K Rufibach
J Rajadas
H Zhang
B Tomooka
W H Robinson
C M Clark
A M Fagan
D R Galasko
D M Holtzman
M Jutel
J A Kaye
C A Lemere
J Leszek
G Li
E R Peskind
J F Quinn
J A Yesavage
J A Ghiso
|
| method: |
biological activity
|
| name: |
Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease.
|
| description: |
Human IgGs from AD patients bound the epitope and protected primary E16 neurons from the amyloidogenic effect of the peptide and increased overall cell viability.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
