Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1865850 |
| description: |
epitope description:P373, R377, Q408, Q432, H433, S442, S464, K467, K489, I491, S492, N497
antigen name:Epidermal growth factor receptor
host organism:Homo sapiens
antibody name:IMC-11F8
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
18275813 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1019635 |
| landingPage: |
http://www.iedb.org/assay/1865850 |
| type: |
Literature
|
| publicationVenue: |
Structure
|
| dates: |
2008
|
| study type: | b cell assays |
| subject species: | Homo sapiens |
| fullName: |
Shiqing Li
Paul Kussie
Kathryn M Ferguson
|
| method: |
x-ray crystallography
|
| name: |
Structural basis for EGF receptor inhibition by the therapeutic antibody IMC-11F8.
|
| description: |
The epitope of Fab IMC-11F8 on the EGF receptor extracellular domain III was determined from the crystal structure of the complex. There are eight sEGFRd3-Fv complexes in the asymmetric unit of this crystal form.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
