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identifier: 1866668
description:
epitope description:S17, I21, Q25, H27, V29, E31, Y32, D33, P34, T35, I36, E37, D38, S39, Y40, Q61, E63, Y64
antigen name:GTPase HRas
host organism:Homo sapiens
antibody name:anti-RAS
aggregation:
instance of dataset
availability:
available
primaryPublications: 17568777
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1018825
landingPage: http://www.iedb.org/assay/1866668
type:
Literature
publicationVenue:
EMBO J
dates:
2007
study type: b cell assays
subject species: Homo sapiens
fullName:
Tomoyuki Tanaka
Roger L Williams
Terence H Rabbitts
method:
binding assay
name:
Tumour prevention by a single antibody domain targeting the interaction of signal transduction proteins with RAS.
description:
Epitope residues are calculated from the structure [PDB: 2UZI] as the antigen residues at 4 Å
distance from the antibody.
The epitope-specific anti-RAS single VH#6 domain (iDab#6) intrabody bound to RRAS in Cos-7 cells.

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