Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1866644 |
| description: |
epitope description:H98, P99, L100, Y101, D116, H119, T143, K191, K194, F195, H248, Y249, R250, K251, W252, K254
antigen name:Prostate-specific antigen
host organism:Mus musculus BALB/c
antibody name:8G8F5
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
18187150 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1018820 |
| landingPage: |
http://www.iedb.org/assay/1866644 |
| type: |
Literature
|
| publicationVenue: |
J Mol Biol
|
| dates: |
2008
|
| study type: | b cell assays |
| subject species: | Homo sapiens |
| fullName: |
René
e Mé
nez
Sandrine Michel
Bruno H Muller
Marc Bossus
Fré
dé
ric Ducancel
Colette Jolivet-Reynaud
Enrico A Stura
|
| method: |
biological activity
|
| name: |
Crystal structure of a ternary complex between human prostate-specific antigen, its substrate acyl intermediate and an activating antibody.
|
| description: |
Epitope residues are calculated from the structure [PDB: 2ZCH] as the antigen residues at 4 Å
distance from the antibody.
The epitope-specific mAb 8G8F5 does not inhibit the enzymatic activity of PSA and does not block zinc-mediated inhibition of PSA enzymatic activity.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
