Characterization of Zaire ebolavirus glycoprotein-specific monoclonal antibodies. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Characterization of Zaire ebolavirus glycoprotein-specific monoclonal antibodies.

Dataset

identifier:	1884076
description:	epitope description:AGNNNTHHQDTGEESASSGKLGLITNTIAGVAGLITGGRRTR antigen name:Envelope glycoprotein host organism:Mus musculus BALB/c
aggregation:	instance of dataset
availability:	available
primaryPublications:	21925951

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1022541
landingPage:	http://www.iedb.org/assay/1884076

Publication

type:	Literature
publicationVenue:	Clin Immunol
dates:	2011

Dimension

study type:	b cell assays
subject species:	Zaire ebolavirus

Person

fullName:	Xiangguo Qiu Judie B Alimonti P Leno Melito Lisa Fernando Ute Strö her Steven M Jones

Data Type

method:	in vivo assay

Study

name:	Characterization of Zaire ebolavirus glycoprotein-specific monoclonal antibodies.
description:	The epitope sequence was deduced and was previously described in Wahl-Jensen et al., J Virol:79(2413) 2005 [PMID:15681442]. Adoptive transfer of the epitope-specific mAb either 1 day before or 1 day after challenge provided complete protection against ZEBOV, including increased survival and lack of weight loss.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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