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identifier: 1885223
description:
epitope description:alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-D-Glc
antigen name:glycolipid
host organism:Mus musculus BALB/c
antibody name:3D9, 6A2, 2C2, 4A11, 2C10, 1G12
aggregation:
instance of dataset
availability:
available
primaryPublications: 2456994
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1012798
landingPage: http://www.iedb.org/assay/1885223
type:
Literature
publicationVenue:
Int J Cancer
dates:
1988
study type: b cell assays
subject species: Homo sapiens
fullName:
N T Brodin
J Dahmé
n
B Nilsson
L Messeter
S Må
rtensson
J Heldrup
H O Sjö
gren
A Lundblad
method:
flow cytometry
name:
Monoclonal antibodies produced by immunization with neoglycoproteins containing Gal alpha 1-4Gal beta 1-4Glc beta-O and Gal alpha 1-4Gal beta 1-4GlcNAc beta-O residues: useful immunochemical and cytochemical reagents for blood group P antigens and a differentiation marker in Burkitt lymphoma and other B-cell malignancies.
description:
The epitope-reactive mAbs bound to the Burkitt lymphoma cell lines Raji and Daudi, but not to a control lymphoblastoid B cell line. MAbs 6A2 and 3D9 stained tumor cells from patients with Burkitt-like lymphoma and patients with acute lymphatic leukemia by flow cytometry and indirect immunofluorescence.

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