Crystal structure of the complex mAb 17.2 and the C-terminal region of Trypanosoma cruzi P2beta protein: implications in cross-reactivity.

Title:

Crystal structure of the complex mAb 17.2 and the C-terminal region of Trypanosoma cruzi P2beta protein: implications in cross-reactivity.

identifier:	1885281
description:	epitope description:EEEDDDMGFGLFD antigen name:Other Trypanosoma cruzi protein host organism:Mus musculus BALB/c antibody name:17.2
aggregation:	instance of dataset
availability:	available
primaryPublications:	22069505

study type:	b cell assays
subject species:	Trypanosoma cruzi

fullName:	Juan Carlos Pizarro Ginette Boulot Graham A Bentley Karina A Gó mez Johan Hoebeke Mireille Hontebeyrie Mariano J Levin Cristian R Smulski

method:	antigen inhibition

name:	Crystal structure of the complex mAb 17.2 and the C-terminal region of Trypanosoma cruzi P2beta protein: implications in cross-reactivity.
description:	The epitope inhibited the binding of mAb 17.2 to HEK cells transfected with ß1-adrenergic receptor (ß1-AR). ß1-AR contains an acidic motif (AESDEA) similar to the epitope.

name:	iedb
homePage:	http://www.iedb.org

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