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Title: An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket.
identifier: 1903111
description:
epitope description:5-[(2-aminobenzimidazol-6-yl)amino]-5-oxopentanoic acid zwitterion
host organism:Mus musculus
antibody name:13G5
aggregation:
instance of dataset
availability:
available
primaryPublications: 19846764
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1019658
landingPage: http://www.iedb.org/assay/1903111
type:
Literature
publicationVenue:
Proc Natl Acad Sci U S A
dates:
2009
study type: b cell assays
subject species:
fullName:
Erik W Debler
Roger Mü
ller
Donald Hilvert
Ian A Wilson
method:
x-ray crystallography
name:
An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket.
description:
The crystal structure of catalytic antibody Fab 13G5 in complex with the epitope was determined by molecular replacement.

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