Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1019492 |
| landingPage: |
http://www.iedb.org/assay/1903833 |
| type: |
Literature
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| publicationVenue: |
J Mol Biol
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| dates: |
2008
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| study type: | b cell assays |
| subject species: |
| fullName: |
Roman C Hillig
Stefanie Urlinger
Jö
rg Fanghä
nel
Bodo Brocks
Cornelia Haenel
Yvonne Stark
Detlev Sü
lzle
Dmitri I Svergun
Siegfried Baesler
Guido Malawski
Dieter Moosmayer
Andreas Menrad
Michael Schirner
Kai Licha
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| method: |
x-ray crystallography
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| name: |
Fab MOR03268 triggers absorption shift of a diagnostic dye via packaging in a solvent-shielded Fab dimer interface.
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| description: |
The crystal structure of Fab MOR03268 in complex with the epitope was determined and solved by molecular replacement. The epitope induced Fab dimer formation. Two different crystal forms of the Fab-epitope complex were identified. The tetragonal crystal form 2, curated here, appeared only after several weeks and contained two Fab molecules in the asymmetric unit bound to the dimerized hapten.
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| name: |
iedb
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| homePage: |
http://www.iedb.org |
