Identification and mapping of linear antigenic determinants of human amyloid ß(1-42) peptide. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Identification and mapping of linear antigenic determinants of human amyloid ß(1-42) peptide.

Dataset

identifier:	1904026
description:	epitope description:FRHDSGY antigen name:Amyloid beta A4 protein host organism:Oryctolagus cuniculus New Zealand White
aggregation:	instance of dataset
availability:	available
primaryPublications:	22181818

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1022685
landingPage:	http://www.iedb.org/assay/1904026

Publication

type:	Literature
publicationVenue:	J Immunoassay Immunochem
dates:	2012

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	Sarada Subramanian Regina D'Souza A N Divya Shree

Data Type

method:	ELISA

Study

name:	Identification and mapping of linear antigenic determinants of human amyloid ß(1-42) peptide.
description:	The epitope was deduced. Overlapping peptides 1-16 and 7-22 were tested to deduce the epitope as the dominant B cell epitope. Immunization with the analog resulting in loss of reactivity, suggesting residues 19, 32, 36, 39, and 42 play a role in presentation of this epitope.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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