Crystal structure of single-domain VL of an anti-DNA binding antibody 3D8 scFv and its active site revealed by complex structures of a small molecule and metals.

Title:

Crystal structure of single-domain VL of an anti-DNA binding antibody 3D8 scFv and its active site revealed by complex structures of a small molecule and metals.

Dataset

identifier:	1904244
description:	epitope description:bis-tris host organism:Mus musculus MLR/lpr antibody name:3D8 VL
aggregation:	instance of dataset
availability:	available
primaryPublications:	18338383

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1019344
landingPage:	http://www.iedb.org/assay/1904244

Publication

type:	Literature
publicationVenue:	Proteins
dates:	2008

Dimension

study type:	b cell assays
subject species:

Person

fullName:	Suk-Youl Park Woo-Ram Lee Suk-Chan Lee Myung-Hee Kwon Yong-Sung Kim Jeong-Sun Kim

Data Type

method:	x-ray crystallography

Study

name:	Crystal structure of single-domain VL of an anti-DNA binding antibody 3D8 scFv and its active site revealed by complex structures of a small molecule and metals.
description:	The crystal structure of the single domain of 3D8 light chain in complex with the epitope was determined, solved by molecular replacement. The crystals were soaked into precipitant solution containing 2 mM CdCl2. There are two molecules in the asymmetric unit. Only one of the two molecules (molA) has a bound BTB molecule.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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