Characterization of an isotype-dependent monoclonal antibody against linear neutralizing epitope effective for prophylaxis of enterovirus 71 infection.

Title:

Characterization of an isotype-dependent monoclonal antibody against linear neutralizing epitope effective for prophylaxis of enterovirus 71 infection.

Dataset

identifier:	1910888
description:	epitope description:KQEKD antigen name:Genome polyprotein host organism:Mus musculus BALB/c antibody name:mAb 53
aggregation:	instance of dataset
availability:	available
primaryPublications:	22279543

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1022776
landingPage:	http://www.iedb.org/assay/1910888

Publication

type:	Literature
publicationVenue:	PLoS One
dates:	2012

Dimension

study type:	b cell assays
subject species:	Human enterovirus 71 NUH0083/SIN/08

Person

fullName:	Xiao Fang Lim Qiang Jia Wei Xin Khong Benedict Yan Balraj Premanand Sylvie Alonso Vincent T K Chow Jimmy Kwang

Data Type

method:	immuno staining

Study

name:	Characterization of an isotype-dependent monoclonal antibody against linear neutralizing epitope effective for prophylaxis of enterovirus 71 infection.
description:	The epitope-specific mAb was shown to cross-react with 11 representative EV71 strains which were shown by sequence alignment to contain the epitope by Western blot and by IFA. The mAb did not cross-react with coxsackievirus A16.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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