Evolution of shape complementarity and catalytic efficiency from a primordial antibody template. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Evolution of shape complementarity and catalytic efficiency from a primordial antibody template.

Dataset

identifier:	1906353
description:	epitope description:1,7,8,9,10,10-hexachloro-4-methyl-4-azatricyclo[5.2.1.0(2,6)]dec-8-ene-3,5-dione host organism:Mus musculus 129 GIX+ antibody name:1E9
aggregation:	instance of dataset
availability:	available
primaryPublications:	10600746

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1019491
landingPage:	http://www.iedb.org/assay/1906353

Publication

type:	Literature
publicationVenue:	Science
dates:	1999

Dimension

study type:	b cell assays
subject species:

Person

fullName:	J Xu Q Deng J Chen K N Houk J Bartek D Hilvert I A Wilson

Data Type

method:	x-ray crystallography

Study

name:	Evolution of shape complementarity and catalytic efficiency from a primordial antibody template.
description:	The crystal structure of catalytic antibody 1E9 Fab in complex with the epitope, a transition state analog, was determined by molecular replacement.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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