Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge.

Dataset

identifier:	1906800
description:	epitope description:Q412, W420, N423, R483, P484, Y485, G523, P525, T526, G530, T534, N540, P544, P545, G547, W549 antigen name:Genome polyprotein host organism:Homo sapiens antibody name:AR1B
aggregation:	instance of dataset
availability:	available
primaryPublications:	18064037

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1022650
landingPage:	http://www.iedb.org/assay/1906800

Publication

type:	Literature
publicationVenue:	Nat Med
dates:	2008

Dimension

study type:	b cell assays
subject species:	Hepatitis C virus subtype 1a

Person

fullName:	Mansun Law Toshiaki Maruyama Jamie Lewis Erick Giang Alexander W Tarr Zania Stamataki Pablo Gastaminza Francis V Chisari Ian M Jones Robert I Fox Jonathan K Ball Jane A McKeating Norman M Kneteman Dennis R Burton

Data Type

method:	ELISA

Study

name:	Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge.
description:	Apparent affinity was measured for the epitope-specific mAb and was defined as the ab concentration required to achieve half-maximal binding to the E1E2 complex.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.