Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1907139 |
| description: |
epitope description:{4)-beta-D-Glc-(1->6)-[alpha-D-NeuNAc-(2->3)-beta-D-Gal-(1->4)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->}n
antigen name:polysaccharide
host organism:Mus musculus BALB/c
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
22101769 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1022637 |
| landingPage: |
http://www.iedb.org/assay/1907139 |
| type: |
Literature
|
| publicationVenue: |
Nat Med
|
| dates: |
2011
|
| study type: | b cell assays |
| subject species: | Streptococcus agalactiae serogroup III M781 |
| fullName: |
Fikri Y Avci
Xiangming Li
Moriya Tsuji
Dennis L Kasper
|
| method: |
in vivo assay
|
| name: |
A mechanism for glycoconjugate vaccine activation of the adaptive immune system and its implications for vaccine design.
|
| description: |
The epitope structure represents the repetitive unit of type III GBS capsular polysaccharide.
The survival of pups born to immunized dams and challenged with type III group B Streptococcus was higher (100%) with the polysacharide-peptide immunization than with polysaccharide-protein conjugate (65%), while a low response (~15%) is obtained with the unconjugated polysaccharide. The peptide-polysaccharide conjugate is stated to be more immunogenic as it is more ordered that the protein-polysaccharide conjugates.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
