Inclusion of a specific T cell epitope increases the protection conferred against foot-and-mouth disease virus in pigs by a linear peptide containing an immunodominant B cell site.

Title:

Inclusion of a specific T cell epitope increases the protection conferred against foot-and-mouth disease virus in pigs by a linear peptide containing an immunodominant B cell site.

Dataset

identifier:	1930401
description:	epitope description:YTASARGDLAHLTTTHARH antigen name:Polyprotein host organism:Sus scrofa Landrace X Large White
aggregation:	instance of dataset
availability:	available
primaryPublications:	22416886

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1022966
landingPage:	http://www.iedb.org/assay/1930401

Publication

type:	Literature
publicationVenue:	Virol J
dates:	2012

Dimension

study type:	b cell assays
subject species:	Foot-and-mouth disease virus

Person

fullName:	Carolina Cubillos Beatriz G de la Torre Juan Bá rcena David Andreu Francisco Sobrino Esther Blanco

Data Type

method:	biological activity

Study

name:	Inclusion of a specific T cell epitope increases the protection conferred against foot-and-mouth disease virus in pigs by a linear peptide containing an immunodominant B cell site.
description:	Epitope immunization of pigs induced neutralizing antibodies to FMDV C-S8c1. Pigs immunized with either the epitope alone or a peptide conjugate containing the epitope and a FMDV T cell epitope AAIEFFEGMVHDSIK were all positive for neutralizing antibodies.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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