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Title: Crystal structure of a non-neutralizing antibody to the HIV-1 gp41 membrane-proximal external region.
identifier: 1917082
description:
epitope description:QQEKNEQELLELDKWASLWN + AMID(N20)
antigen name:Envelope glycoprotein gp160
host organism:Mus musculus BALB/c
antibody name:13H11
aggregation:
instance of dataset
availability:
available
primaryPublications: 21076400
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1022157
landingPage: http://www.iedb.org/assay/1917082
type:
Literature
publicationVenue:
Nat Struct Mol Biol
dates:
2010
study type: b cell assays
subject species: Human immunodeficiency virus 1
fullName:
Nathan I Nicely
S Moses Dennison
Leonard Spicer
Richard M Scearce
Garnett Kelsoe
Yoshihiro Ueda
Haiyan Chen
Hua-Xin Liao
S Munir Alam
Barton F Haynes
method:
surface plasmon resonance (SPR)
name:
Crystal structure of a non-neutralizing antibody to the HIV-1 gp41 membrane-proximal external region.
description:
The N-terminus is acetylated and the C-terminus is amidated.
The affinity of Fab 13H11 for the epitope was determined by SPR.

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