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Title: Biotin sulfone tagged oligomannosides as immunogens for eliciting antibodies against specific mannan epitopes.
identifier: 1922213
description:
epitope description:alpha-D-Manp-(1->3)-alpha-D-Manp-(1->2)-alpha-D-Manp-(1->2)-alpha-D-Manp
antigen name:mannan
host organism:Mus musculus BALB/c
aggregation:
instance of dataset
availability:
available
primaryPublications: 22326546
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1022830
landingPage: http://www.iedb.org/assay/1922213
type:
Literature
publicationVenue:
Bioorg Med Chem
dates:
2012
study type: b cell assays
subject species: Candida albicans
fullName:
Guillaume Despras
Raymond Robert
Boualem Sendid
Emeline Machez
Daniel Poulain
Jean-Maurice Mallet
method:
ELISA
name:
Biotin sulfone tagged oligomannosides as immunogens for eliciting antibodies against specific mannan epitopes.
description:
This epitope is found in the mannan of S. cerevisiae and is found also in C. albicans under certain conditions of growth.
The epitope-specific antisera IgM reacted with mannan from C. albicans in ELISA. The reaction was lower with mannan extracted from cultures growth at pH 7. However when the mannan was extracted from C. albicans grown at pH 2, a condition known to induce a higher expression of the epitope, a higher reactivity of the mouse serum was observed.

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