Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1022813 |
| landingPage: |
http://www.iedb.org/assay/1927742 |
| type: |
Literature
|
| publicationVenue: |
Vaccine
|
| dates: |
2012
|
| study type: | b cell assays |
| subject species: | Ricinus communis |
| fullName: |
Joanne M O'Hara
Kevin Whaley
Michael Pauly
Larry Zeitlin
Nicholas J Mantis
|
| method: |
biological activity
|
| name: |
Plant-based expression of a partially humanized neutralizing monoclonal IgG directed against an immunodominant epitope on the ricin toxin A subunit.
|
| description: |
An epitope-specific chimeric derivative of the mAb GD12 (cGD12), in which the murine heavy (VH) and light chain (VL) variable regions were fused to a human IgG1 framework, was shown to neutralize ricin toxin in vitro. Similar results were obtined with an unmodified version of the mAb.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
