Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1927725 |
| description: |
epitope description:(4Z)-2,8:7,12:11,15:14,18:17,22-pentaanhydro-4,5,6,9,10,13,19,20,21-nonadeoxy-L-arabino-L-allo-L-allo-docosa-4,9,20-trienitol
antigen name:ciguatoxin CTX3C
host organism:Mus musculus BALB/c
antibody name:10C9
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
18463096 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1019584 |
| landingPage: |
http://www.iedb.org/assay/1927725 |
| type: |
Literature
|
| publicationVenue: |
J Biol Chem
|
| dates: |
2008
|
| study type: | b cell assays |
| subject species: | Gambierdiscus toxicus |
| fullName: |
Mihoko Ui
Yoshikazu Tanaka
Takeshi Tsumuraya
Ikuo Fujii
Masayuki Inoue
Masahiro Hirama
Kouhei Tsumoto
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| method: |
calorimetry
|
| name: |
How protein recognizes ladder-like polycyclic ethers. Interactions between ciguatoxin (CTX3C) fragments and its specific antibody 10C9.
|
| description: |
The association constant for 10C9 Fab binding to the epitope was determined by isothermal titration calorimetry. The Tm for for the epitope-10C9 Fab complex was higher (Tm = 86.8ºC) than that of the ligand free form (Tm = approximately 78ºC), as determined by differential scanning calorimetry.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
