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Title: Evaluation of novel Streptococcus pyogenes vaccine candidates incorporating multiple conserved sequences from the C-repeat region of the M-protein.
identifier: 1927888
description:
epitope description:KQAEDKVKASREAKKQVEKALEQLEDKVK
host organism:Mus musculus B10.BR
aggregation:
instance of dataset
availability:
available
primaryPublications: 22265945
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1022848
landingPage: http://www.iedb.org/assay/1927888
type:
Literature
publicationVenue:
Vaccine
dates:
2012
study type: b cell assays
subject species:
fullName:
Michelle J Bauer
Melina M Georgousakis
Therese Vu
Anna Henningham
Andreas Hofmann
Mandy Rettel
Louise M Hafner
Kadaba S Sriprakash
David J McMillan
method:
ELISA
name:
Evaluation of novel Streptococcus pyogenes vaccine candidates incorporating multiple conserved sequences from the C-repeat region of the M-protein.
description:
The epitope sequence was provided in cited reference Georgousakis et al. Vaccine 27:6799-6806 [PMID: 19729086].
Sera from mice immunized with the epitope recognized the vaccine antigen. Isotype analysis showed IgG1, IgG2b and IgG2a, but very little IgG3.

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