Evaluation of novel Streptococcus pyogenes vaccine candidates incorporating multiple conserved sequences from the C-repeat region of the M-protein.

Title:

Evaluation of novel Streptococcus pyogenes vaccine candidates incorporating multiple conserved sequences from the C-repeat region of the M-protein.

Dataset

identifier:	1927902
description:	epitope description:KQAEDKVKASREAKKQVEKALEQLEDKVK host organism:Mus musculus B10.BR
aggregation:	instance of dataset
availability:	available
primaryPublications:	22265945

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1022848
landingPage:	http://www.iedb.org/assay/1927902

Publication

type:	Literature
publicationVenue:	Vaccine
dates:	2012

Dimension

study type:	b cell assays
subject species:

Person

fullName:	Michelle J Bauer Melina M Georgousakis Therese Vu Anna Henningham Andreas Hofmann Mandy Rettel Louise M Hafner Kadaba S Sriprakash David J McMillan

Data Type

method:	flow cytometry

Study

name:	Evaluation of novel Streptococcus pyogenes vaccine candidates incorporating multiple conserved sequences from the C-repeat region of the M-protein.
description:	The epitope sequence was provided in cited reference Georgousakis et al. Vaccine 27:6799-6806 [PMID: 19729086]. Sera from mice immunized with the epitope recognized and bound to the surface of S. pyogenes 88-30-infected cells. Sera also recognized cells infected with the M1 and ES-61 strains.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.

Related Publications

Feedback?