A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity.

Dataset

identifier:	1927911
description:	epitope description:beta-D-fructopyranose host organism:Homo sapiens antibody name:2G12
aggregation:	instance of dataset
availability:	available
primaryPublications:	20852065

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1022156
landingPage:	http://www.iedb.org/assay/1927911

Publication

type:	Literature
publicationVenue:	Proc Natl Acad Sci U S A
dates:	2010

Dimension

study type:	b cell assays
subject species:

Person

fullName:	Katie J Doores Zara Fulton Vu Hong Mitul K Patel Christopher N Scanlan Mark R Wormald M G Finn Dennis R Burton Ian A Wilson Benjamin G Davis

Data Type

method:	ELISA

Study

name:	A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity.
description:	The epitope is a mimotope of D-mannose contained as a terminal mannoside of the D1 arm of the high-mannose glycan on HIV-1 gp120. The epitope-reactive mAb 2G12 bound to gp120 from HIV-1 (JR CSF).

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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