Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1928230 |
| description: |
epitope description:V160, T161, A162, M163, S168, S170, V171, E172, V173, K174, P176, D177, G179, E180, K291, R293
antigen name:Genome polyprotein
host organism:Pan troglodytes
antibody name:5H2
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
22139356 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1022774 |
| landingPage: |
http://www.iedb.org/assay/1928230 |
| type: |
Literature
|
| publicationVenue: |
EMBO J
|
| dates: |
2012
|
| study type: | b cell assays |
| subject species: | Dengue virus 4 |
| fullName: |
Joseph J B Cockburn
M Erika Navarro Sanchez
Ana P Goncalvez
Elena Zaitseva
Enrico A Stura
Carlos M Kikuti
Sté
phane Duquerroy
Philippe Dussart
Leonid V Chernomordik
Ching-Juh Lai
Felix A Rey
|
| method: |
biological activity
|
| name: |
Structural insights into the neutralization mechanism of a higher primate antibody against dengue virus.
|
| description: |
The epitope-specific mAb 5H2 inhibited the fusion of DENV-4 virions with liposomes, that mimic the phospholipid composition of late endosomes, in a dose-dependent manner.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
