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Title: Genetic mapping of a highly variable norovirus GII.4 blockade epitope: potential role in escape from human herd immunity.
identifier: 1929502
description:
epitope description:V294, S296, H297, D298, T368, N372
antigen name:Capsid protein VP1
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 22090110
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1022707
landingPage: http://www.iedb.org/assay/1929502
type:
Literature
publicationVenue:
J Virol
dates:
2012
study type: b cell assays
subject species: Norovirus genogroup 2 Camberwell 1890
fullName:
Kari Debbink
Eric F Donaldson
Lisa C Lindesmith
Ralph S Baric
method:
biological activity
name:
Genetic mapping of a highly variable norovirus GII.4 blockade epitope: potential role in escape from human herd immunity.
description:
1988 human outbreak serum was shown to inhibit the interaction of the GII.4-1987 VLP with the H3 histo-blood group antigen suggesting that the epitope contributes (though weakly) to the global GII.4-1987 blockade response in humans.

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