A highly alpha-stereoselective synthesis of oligosaccharide fragments of the Vi antigen from Salmonella typhi and their antigenic activities.

Title:

A highly alpha-stereoselective synthesis of oligosaccharide fragments of the Vi antigen from Salmonella typhi and their antigenic activities.

identifier:	1929395
description:	epitope description:3-O-Ac-alpha-D-GalpANAc-(1->4)-3-O-Ac-alpha-D-GalpANAc antigen name:[4)-3-O-Ac-alpha-D-GalpANAc(1->]n host organism:Oryctolagus cuniculus
aggregation:	instance of dataset
availability:	available
primaryPublications:	22095754

study type:	b cell assays
subject species:	Salmonella enterica subsp. enterica serovar Typhi

fullName:	Lin Yang Jingjing Zhu Xiu-Jing Zheng Guihua Tai Xin-Shan Ye

method:	antigen inhibition

name:	A highly alpha-stereoselective synthesis of oligosaccharide fragments of the Vi antigen from Salmonella typhi and their antigenic activities.
description:	The epitope is a disaccharide of GalANAc acetylated at position 3. It was synthesyzed to resemble the sugars contained in the Vi capsular polysaccharide of S. typhi, a linear homopolymer of (1&rarr 4)-alpha-D-GalpANAc, variably O-acetylated at the 3-position. The epitope competed weakly the binding of anti-Vi antisera to solid-phase Vi polysaccharide.

name:	iedb
homePage:	http://www.iedb.org

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