Bacterial Toxin Fusion Proteins Elicit Mucosal Immunity against a Foot-and-Mouth Disease Virus Antigen When Administered Intranasally to Guinea Pigs.

Title:

Bacterial Toxin Fusion Proteins Elicit Mucosal Immunity against a Foot-and-Mouth Disease Virus Antigen When Administered Intranasally to Guinea Pigs.

Dataset

identifier:	1929717
description:	epitope description:RYSRNAVPNLRGDLQVLAQKVART antigen name:Polyprotein host organism:Cavia porcellus Duncan-Hartley
aggregation:	instance of dataset
availability:	available
primaryPublications:	22312350

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1022816
landingPage:	http://www.iedb.org/assay/1929717

Publication

type:	Literature
publicationVenue:	Adv Virol
dates:	2011

Dimension

study type:	b cell assays
subject species:	Foot-and-mouth disease virus (strain O1) (O1BFS)

Person

fullName:	Sreerupa Challa Steven M Szczepanek Debra Rood Roger W Barrette Lawrence K Silbart

Data Type

method:	ELISA

Study

name:	Bacterial Toxin Fusion Proteins Elicit Mucosal Immunity against a Foot-and-Mouth Disease Virus Antigen When Administered Intranasally to Guinea Pigs.
description:	The epitope sequence was provided in cited reference Challa et al. Vaccine 2007 25:3328-3337 [PMID:17276557]. Epitope-specific IgA from nasal wash was detected at week 4 and 6. Responses elicited by the immungon contain the ntPE were slightly higher. No response was observed following s.c. injection.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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