A pan-H1 anti-hemagglutinin monoclonal antibody with potent broad-spectrum efficacy in vivo. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

A pan-H1 anti-hemagglutinin monoclonal antibody with potent broad-spectrum efficacy in vivo.

Dataset

identifier:	1938320
description:	epitope description:A388 antigen name:Hemagglutinin host organism:Mus musculus BALB/c
aggregation:	instance of dataset
availability:	available
primaryPublications:	22491456

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1023096
landingPage:	http://www.iedb.org/assay/1938320

Publication

type:	Literature
publicationVenue:	J Virol
dates:	2012

Dimension

study type:	b cell assays
subject species:	Influenza A virus

Person

fullName:	Gene S Tan Florian Krammer Dirk Eggink Alita Kongchanagul Thomas M Moran Peter Palese

Data Type

method:	in vivo assay

Study

name:	A pan-H1 anti-hemagglutinin monoclonal antibody with potent broad-spectrum efficacy in vivo.
description:	Adoptive transfer of the epitope-specific mAb was shown to provide preexposure protection against viral infection as measured by weight loss and survival. Viral lung titers were also shown to be reduced.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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