Antibodies directed to drug epitopes to investigate the structure of drug-protein photoadducts. Recognition of a common photobound substructure in tiaprofenic acid/ketoprofen cross-photoreactivity.

Title:

Antibodies directed to drug epitopes to investigate the structure of drug-protein photoadducts. Recognition of a common photobound substructure in tiaprofenic acid/ketoprofen cross-photoreactivity.

Dataset

identifier:	1939077
description:	epitope description:tiaprofenic acid host organism:Oryctolagus cuniculus
aggregation:	instance of dataset
availability:	available
primaryPublications:	11712905

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1011356
landingPage:	http://www.iedb.org/assay/1939077

Publication

type:	Literature
publicationVenue:	Chem Res Toxicol
dates:	2001

Dimension

study type:	b cell assays
subject species:

Person

fullName:	A Lahoz D Herná ndez M A Miranda J Pé rez-Prieto I M Morera J V Castell

Data Type

method:	ELISA

Study

name:	Antibodies directed to drug epitopes to investigate the structure of drug-protein photoadducts. Recognition of a common photobound substructure in tiaprofenic acid/ketoprofen cross-photoreactivity.
description:	The 4-(5-ethyl-2-thienyl)-4-oxobutanoic acid-specific IgG fraction failed to react with epitope-BSA chemical conjugates as well as with epitope-BSA photoadducts, by ELISA and dot-blot.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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