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Title: Delivery of a DNA vaccine for Alzheimer's disease by electroporation versus gene gun generates potent and similar immune responses.
identifier: 1931178
description:
epitope description:DAEFRHDSGYE
antigen name:Amyloid beta A4 protein
host organism:Mus musculus C57BL/6
aggregation:
instance of dataset
availability:
available
primaryPublications: 22301697
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1023031
landingPage: http://www.iedb.org/assay/1931178
type:
Literature
publicationVenue:
Neurodegener Dis
dates:
2012
study type: b cell assays
subject species: Homo sapiens
fullName:
Hayk Davtyan
Anahit Ghochikyan
Nina Movsesyan
Barry Ellefsen
Irina Petrushina
David H Cribbs
Drew Hannaman
Claire F Evans
Michael G Agadjanyan
method:
antigen inhibition
name:
Delivery of a DNA vaccine for Alzheimer's disease by electroporation versus gene gun generates potent and similar immune responses.
description:
Epitope-specific antisera from mice immunized with the DepVac vaccine using either electroporation (EP) i.m. or gene gun (GG) intradermal delivery bound to ß-amyloid plaques in cortical brain sections from AD patients. Preabsorption of the antisera with Aß42 peptide blocked the staining.

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